When Asajj Ventress was betrayed and broken, Talzin took Ventress in and when Asajj told her the whole story, she immediately had a plan. Talzin got two other Nightsisters, Naa'leth and Karis, to assist Asajj in an assassination attempt. Using magic to make the trio invisible and arming them with Jedilightsabers and a special poisonous dart, Talzin sent them to attack Dooku at his estate on Serenno. When the attempt failed Mother Talzin used the attack as oppurtunity to offer Dooku a new "apprentice" manipulating the Sith Lord's new found paranoia brought about by his nearly being killed in his own home. When Ventress found a candidate, Savage Opress, he would become Dooku's new "apprentice", but his real job was to eliminate Dooku for Talzin and Ventress.